Table 3.

Median histopathologic scores for the lung and heart tissues from each group

	Control group	Day 1 group	Day 2 group	Day 7 group	p value
	n = 7	n = 7	n = 7	n = 7
Lung
Interstitial edema	0 (0 – 1)	1 (1 – 2)	1 (1 – 2)	2 (2 – 3)	<0,001
Hemorrhage	1 (0 – 1)	2 (2 – 2)	2 (2 – 2)	3 (2 – 3)	<0,001
Epithelial injury	0 (0 – 1)	1 (1 – 2)	1 (1 – 2)	2 (1 – 2)	<0,001
Hyalin membrane formation	0 (0 – 0)	1 (1 – 1)	1 (1 – 2)	2 (1 – 2)	<0,001
Neutrophil infiltration	0 (0 – 1)	2 (1 – 2)	2 (1 – 2)	2 (2 – 3)	<0,001
Emphysematous changes	0 (0 – 1)	1 (1 – 2)	2 (1 – 2)	2 (2 – 3)	<0,001
Lymphocytic infiltration	1 (0 – 1)	1 (1 – 2)	2 (1 – 2)	2 (1 – 2)	0,017
Total injury score	2 (1 – 4)	9 (8 – 13)	11 (9 – 13)	15 (11 – 18)	<0,001
Heart
Myocardial edema	0 (0 – 0)	1 (1 – 2)	1 (1 – 2)	2 (2 – 2)	<0,001
Myocytolysis	0 (0 – 1)	1 (1 – 2)	2 (1 – 2)	3 (3 – 3)	<0,001
Focal hemorrhage	0 (0 – 1)	1 (1 – 2)	2 (1 – 2)	3 (3 – 3)	<0,001
Leukocytic infiltration	0 (0 – 0)	1 (0 – 2)	1 (1 – 2)	2 (1 – 2)	<0,001
Loss of cross striation	0 (0 – 0)	1 (1 – 1)	1 (1 – 1)	2 (1 – 2)	<0,001
Total injury score	0 (0 – 2)	5 (4 – 9)	7 (6 – 8)	11 (10 – 12)	<0,001

Median (Min - Max).