Table 1.
Studies included in the pooled analysis
| Author(Year) | Sample size(n) | Age of participants | Dosage | Location | Quality score | Risk Ratio | %Weight using FEM* |
|---|---|---|---|---|---|---|---|
| Madhi et al. (2011) [19] |
547 |
<4 months |
10–20 mg/kg |
South Africa and Botswana |
5A |
0.98(0.7,1.39) |
32.4% |
| Madhi et al. (2011) [19] |
806 |
<4 months |
10–20 mg/kg |
South Africa and Botswana |
5A |
0.86(0.57,1.29) |
22.8% |
| Zar et al. (2007) [18] |
263 |
<51 months |
10(8–12)mg/kg |
South Africa |
5A |
0.28(0.1,0.78) |
3.6% |
| Gupta et al. (1993) [24] |
167 |
5–15 years |
15 mg/kg |
India |
1D |
0.61(0.3,1.25) |
7.5% |
| Debre et al. (1973) [22] |
2,307 |
5–14 years |
5–15 mg/kg |
France |
1D |
0.40(0.15,1.05) |
4.0% |
| Egsmose et al. (1965) [20] |
406 |
0–15 years |
5–10 mg/kg |
Kenya |
5A |
0.38(0.16,0.88) |
5.2% |
| Comstock et al. (1962) [23] |
3,074 |
2 months–15 years |
4–8 mg/kg |
Alaska |
5A |
0.33(0.07,1.64) |
1.5% |
| Mount et al. (1961) [25] |
2,750 |
0–15 years |
4–6 mg/kg |
USA, Canada, Mexico |
5A |
0.40(0.27,0.61) |
22.9% |
| Total | 10,320 | 100% |
*FEM-Fixed Effects Model.