Table 2. Published studies on primary chemotherapy in patients with seminomatous GCT.
| Author (Year) | Number of patients with seminoma | Residual disease | Necrosis/scar |
|---|---|---|---|
| Chong et al (1986) [8] | 5 | 1 (20%) | 4 (80%) |
| Greist et al (1984) [7]a | 1 | NA | NA |
| Ng (1997) [12] | 1b | 0 | 1b |
| Geldart et al (2002) [13] | 18 | 3 (16.7%) | 15 (83.3%) |
| Ramani et al (2008) [16] | 13 | 0 | 13 (100%) |
| Miller et al (2012) [17]c | 6 | 4 | 2 (33.3%) |
| Total | 43(44)d | 8 (18.6%) | 35 (81.3%) |
a
Details of this subgroup were not available.
b
No orchidectomy was performed after complete response to chemotherapy detected on imaging.
c
By personal contact.
d
No details were available from one study by Griest whether there was residual disease or necrosis and hence analysis was done for 43 patients.
NA: Not available.