Table 5.
Comparison of the clinical characteristics of chronic hepatitis C patients with or without hepatic steatosis (≥5%)
| |
|
Steatosis (<5%) |
|
|
Steatosis (≥5%) |
|
|
|---|---|---|---|---|---|---|---|
| |
|
n = 59 |
|
|
n = 18 |
|
|
| Factor | Mean or number | Maximum | Minimum | Mean or number | Maximum | Minimum | P value * |
| Age (years) |
55.2 |
76 |
20 |
59.1 |
69 |
33 |
0.257 |
| Sex (male/female) |
26/33 |
|
|
5/13 |
|
|
0.217 |
| Body mass index (kg/m2) |
22.3 |
30.1 |
16.4 |
23.8 |
32.2 |
19.9 |
0.800 |
| Platelet count (×104/μl) |
18.3 |
41.9 |
7.4 |
17.1 |
36.2 |
5.4 |
0.434 |
| Total cholesterol (mg/dl) |
171.4 |
295 |
84 |
168.4 |
222 |
114 |
0.814 |
| Albumin (g/dl) |
4.3 |
5.1 |
3.3 |
4.0 |
4.9 |
2.9 |
0.023 |
| ALT (IU/l) |
63.1 |
244 |
13 |
69.1 |
191 |
20 |
0.125 |
| γ-GTP (IU/l) |
40.6 |
239 |
12 |
81.4 |
468 |
12 |
0.010 |
| Diabetes (absent/present) |
50/9 |
|
|
10/8 |
|
|
0.009 |
| Fasting plasma glucose (mg/dl) |
95.9 |
196 |
72 |
100.8 |
150 |
80 |
0.145 |
| Hemoglobin A1c (%) |
5.3 (n = 57) |
7.6 |
4.6 |
5.6 |
7.1 |
4.7 |
0.084 |
| Leptin (ng/ml) |
7.0 |
21.8 |
1.0 |
9.6 |
17.3 |
3.5 |
0.006 |
| Adiponectin (ng/ml) |
9.3 |
27.3 |
1.1 |
8 |
26.1 |
1.7 |
0.493 |
| Resistin (ng/ml) |
8.1 |
27.6 |
2.5 |
9.9 |
17.5 |
4 |
0.042 |
| AIM (μg/ml) |
1.37 |
4.56 |
0.41 |
1.43 |
6.44 |
0.72 |
0.290 |
| Hyaluronic acid (ng/ml) | 71.9 (n = 57) | 292.7 | 10 | 171.6 | 636.0 | 11.2 | 0.021 |
*Calculated by Chi-square test for categorical variables or Mann–Whitney U test for continuous variables.
ALT, alanine aminotransferase; γGTP, γ-glutamyl transpeptidase; HOMA-IR, homeostasis model assessment-insulin resistance; AIM, apoptosis inhibitor of macrophage.