Table 2.
Two dimensional echocardiographic findings comparision of two groups before and after first dose Levosimendan and at sixth month follow up.
| Echocardiographic variables | Single dose | Repeated | ||||
|---|---|---|---|---|---|---|
| Pre-treatment | Post-treatment day 3 | 6. month | Pre-treatment | Post-treatment day 3 | 6. month | |
| LVESV (ml) | 155.8±40.0 | 138.1±40.0* | 155.5±40.0# | 159.3±43.1 | 142.4±64* | 138±40.2#,§,£ |
| LVEDV (ml) | 212.5±34.9 | 212.2±35.2 | 212.6±35.4 | 221.9±58.8 | 221.7±58.3 | 216.8±38.3#,§,£ |
| MPI | 1.08±0.19 | 0.88±0.16* | 1.07±0.18# | 1.11±0.2 | 0.94±0.2* | 0.92±0.1#,§,£ |
| Sm (cm/s) | 8.3±0.8 | 10.08±2.0* | 8.2±1.0# | 8.03±1.0 | 9.8±1.8* | 9.6±1.01#,§,£ |
| LVEF (%) | 29.7±2.7 | 33.4±3.2* | 29.4±3.1# | 29.1±3.3 | 32.4±4.4* | 33.7±3.4#,§,£ |
LVESV – left ventricular end sistolic volume; LVEDV – left ventricular end diastolic volume; Sm – peak systolic tissue Doppler velocity at lateral corner of mitral annulus; LVEF – left ventricular ejection fraction.
*
p<0.05 intra-group comparison of values before and after initial levosimendan infusion.
#
p<0.05 intra-group comparison of values after initial levosimendan infusion and values at 6. month.
§
p<0.05 intra-group comparison of values before initial levosimendan infusion and values at 6. month.
£
p<0.05 inter-group comparison of values at 6. month.