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. 2014 Feb 22;20:297–302. doi: 10.12659/MSM.889865

Figure 2.

Figure 2

Th1 cytokine production. Cytokine production from MLN MNCs and splenic MNCs. These MNCs were cultured with medium (negative control, none) or specific allergen (Df). AS mice show significant increases in IFN-γ both in MLNs and splenic MNCs. LTRA inhibits this increase only for IFN-γ production of MLNs. LTRA fails to inhibit the overproduction of IFN-γ from splenic MNCs and IL-2. Systemic steroid inhibits IFN-γ and IL-2 production from MLNs. Bars represents mean (n=12 for each) ±SEM. # p<0.01 vs. Cont, * p<0.05 and ** p<0.01 vs. AS.