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. 2014 Feb 21;9:1039–1048. doi: 10.2147/IJN.S58270

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© 2014 Chen et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Expression of HER2 and hormone receptors in breast cancer subtypes by total HER2 load or hormone receptors. Expression of estrogen receptor (A) and progesterone receptor (B) in three subtypes identified by total HER2 load previously. Expression of TH2 in new subtype classification by quantitative analysis of hormone receptors based on quantum dot nanotechnology (C) and by conventional classification using traditional methods (D).

Abbreviations: CISH, chromogenic in situ hybridization; HTH2&CISH+, high total HER2 load (HTH2) and CISH-positive; HTH2&CISH−, HTH2 and CISH negative; LTH2, low TH2; HHR, high hormone receptor expression; LHR, low hormone receptor expression; NHR, negative hormone receptor expression; TH2, total HER2 load; HER2, human epidermal growth factor receptor 2; ER, estrogen receptor; PR, progesterone receptor.