Table 1.

Nucleotide diversity and neutrality tests for CREB1 and three neighboring genes in human populations

Region	La	Pop	Nb	Sc	θwd	πe	Tajima’s D	Fu and Li’s D*	Fu and Li’s D	Fu and Li’s F*	Fu and Li’s F	Fay and Wu’s H
CREB1	85.4	CHB	97	128	2.6	1.4	−1.37	−5.57	−5.89	−4.30	−4.40	−0.18
		CEU	85	206	4.2	3.3	−0.68	−2.28	−2.34	−1.82	−1.81	−3.92
FAM119A	45.3	CHB	97	56	2.1	1.4	−0.99	−3.31	−3.50	−2.75	−2.85	−2.20
		CEU	85	101	3.9	3.6	−0.25	−1.51	−1.49	−1.12	−1.08	−3.42
CCNYL1	50.3	CHB	97	152	5.2	8.7	2.14	−0.64	−0.71	0.81	0.83	−7.18
		CEU	85	161	5.6	2.9	−1.53	0.73	0.78	−0.39	−0.42	−127.4
FZD5	7.0	CHB	97	18	4.4	4.5	0.05	−1.03	−1.07	−0.73	−0.75	0.65
		CEU	85	19	4.8	3.9	−0.52	−0.33	−0.36	−0.49	−0.51	−2.81

P-value was obtained by coalescent simulations using human demographic history incorporating human best-fit model. Marginally significant P-values (0.05<P<0.1) are in marked italics, significant P-values (0.01<P<0.05) are in bold, and the highly significant P-values (P<0.01) are in bold and underlined.

^aLength of analyzed sequenced region (kb).

^bSample size.

^cNumber of segregating sites.

^dWatterson’s θ estimation per site (× 10⁻⁴).

^eNucleotide diversity per site (× 10⁻⁴).