Skip to main content
. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Clin Endocrinol (Oxf). 2013 Sep 20;80(4):554–561. doi: 10.1111/cen.12316

Figure 2.

Figure 2

Figure 2

a: Representative dissolution profiles for DIURF-001 and DIURF-006. DIURF-001 has a sustained release coat and demonstrates sustained release in vitro whereas DIURF-006 has no sustained release coat and shows delayed but immediate release in vitro. 2b: PK profile for immediate release hydrocortisone (HC), DIURF-002 and DIURF-006 in dogs (Geomean ±SEM). DIURF-006 which has no sustained coating shows much better bioavailability than DIURF-002 which has sustained coating confirming that the sustained coating is the cause of reduced bioavailability.