Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2015 Apr 1.

Published in final edited form as: Clin Endocrinol (Oxf). 2013 Sep 20;80(4):554–561. doi: 10.1111/cen.12316

(a) Dose response of DIURF-006; 5, 10, & 20mg (Geomean ± SEM); (b) Dose proportionality for DIURF-006; 5, 10, & 20mg AUC (Geomean ± SD). Dotted line represents the regression line: Slope: 0.69, 95% CI 0.65-0.73; (c) Twice daily dosing at 23:00 & 07:00h with DIURF-006; 20 and 10mg in dexamethasone suppressed healthy male volunteers.

(a) Dose response of DIURF-006; 5, 10, & 20mg (Geomean ± SEM); (b) Dose proportionality for DIURF-006; 5, 10, & 20mg AUC (Geomean ± SD). Dotted line represents the regression line: Slope: 0.69, 95% CI 0.65-0.73; (c) Twice daily dosing at 23:00 & 07:00h with DIURF-006; 20 and 10mg in dexamethasone suppressed healthy male volunteers.