Table 3. 5-yr hazard ratios of death at different staging spirometry thresholds.

	Mild	Moderate	Severe	Very severe	P
GOLD	>80%1 (ref.)	51–80%2.51 (1.83–3.44)	30–49%5.06 (3.71–6.90)	<30%7.83 (5.65–10.87)	<0.001
Old ATS (BODE)	≥65%1 (ref.)	50–64%1.95 (1.61–2.35)	36–49%3.02 (2.53–3.62)	≤35%4.62 (3.87–5.53)	<0.001
COCOMIX	≥70%1 (ref.)	56–69%1.91 (1.51–2.41)	35–55%3.40 (2.76–4.20)	≤35%5.57 (4.48–6.91)	<0.001

GOLD: Global Obstructive Lung Disease classification. ATS: American Thoracic Society classification. BODE: Body Mass Index, Obstruction (measured with old ATS classification), Dyspnea and Exercise. Hazard Ratios and 95% Confidence Intervals between different cutoffs of the COCOMIX study, GOLD, and BODE classifications.