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. 2014 Feb 27;9(2):e90005. doi: 10.1371/journal.pone.0090005

Figure 4. Effects induced by systemic delivery of miR-34a in MM xenografts.

Figure 4

miR-34a q-RT-PCR A) and q-RT-PCR of NOTCH1 mRNA expression B) at the end of observation of animal treatments with SNALP miR-34a formulation and SNALP miR-NC as control, in retrieved xenograft SKMM-1 tumors. The results are shown as average of miR-34a or NOTCH1 mRNA expression level after normalization with RNU44 or GAPDH, respectively, and ΔΔCt calculations. Data represent the average of 3 independent experiments ±SD. (*) P<0.05, (**) P<0.01.