Table 2. TP53 status in gastric cancer cell lines.
base change, position | Effect | codon72 | |
Kato-III | NA | NA | NA |
KE39 | G to T (GTG to TTG) | Val to Leu | Arg/Arg |
exon8, codon272 | |||
MKN74 | A to C (ATC to CTC) | Ile to Leu | Arg/Arg |
exon7, codon251 | |||
MKN7 | wt | wt | Arg/Arg |
NUGC4 | wt | wt | Arg/Pro |
IWT-1 | C deletion (TCC to TCT) | Frameshift | Arg/Arg |
exon7, codon241 | |||
GSS | T to G (CTT to CGT) | Leu to Arg | Pro/Pro |
exon6, codon194 | |||
GCIY | T to G (CAT to CAG) | His to Gln | Pro/Pro |
exon5, codon179 | |||
MKN45 | wt | wt | Pro/Pro |
NA, Not applicable; wt, wild type.