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(Panel A) Predicted cleavage sites in rat apoE using trypsin, AspN or GluC based on PeptideCutter (web.expasy.org/peptide_cutter/). (Panel B) MALDI TOF MS pattern of enzyme-digested apoE peptides as described under EXPERIMENTAL PROCEDURES: Panel (i) Trypsin, Panel (ii) AspN, Panel (iii) GluC, and, Panel (iv) AspN + GluC.
