Fig. 1.

Study design. Patients received three mandatory IVIG infusions at 3- or 4-week intervals (times for 4-week intervals are shown in brackets), followed by 24 weekly SCIG infusions during the wash-in/wash-out period (Weeks 1–12) and SCIG efficacy period (Weeks 13–25). There were two follow-up visits: completion visit (Week 25) and viral safety follow-up visit 12–17 weeks after completion. The horizontal curve schematically represents the expected fluctuations of serum IgG levels before (dashed curve) and during the SCIG efficacy period (solid curve)