Table 3.
Correlations Between Midexposure Change in HRV and Postexposure Change in ECG Measures of Ventricular Repolarization (ECG Values Limited to 1–4h of Postexposure)
| HRV parameter | Exposure hour | ECG parameter | Postexposurea hour | r | p value |
|---|---|---|---|---|---|
| 3 | Tp-Te | 1 | 0.7 | 0.03 | |
| SDNN | Recovery | Tp-Te | 2 | 0.66 | 0.04 |
| ST area | 2 | 0.62 | 0.06 | ||
| 4 | Tp-Te | 1–4 | 0.67 | 0.03 | |
| Triangular index | ST amplitude | 1–4 | 0.6 | 0.06 | |
| Tp-Te | 4 | 0.74 | 0.01 | ||
| T amplitude | 4 | 0.69 | 0.03 | ||
| ST amplitude | 4 | 0.66 | 0.04 | ||
| Recovery | T amplitude | 1–4 | 0.63 | 0.05 | |
| Tp-Te | 1–4 | 0.61 | 0.06 | ||
| T amplitude | 2 | 0.67 | 0.03 | ||
| ST area | 4 | 0.66 | 0.04 | ||
| Tp-Te | 4 | 0.62 | 0.05 |
Notes. Change in HRV during individual hours of exposure (relative to baseline) significantly correlated with a subsequent change in ECG during 1–4h of postexposure. r indicates Pearson correlation coefficient. N = 5–6 per group.
aWhen animals were monitored in home cages.