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Dock of ORG27569 (lime green) at the WT CB1R (inactive) model. The view is from the lipid bilayer looking toward TMH6-7. The EC ends of TMH6-7 and the EC-3 loop have been omitted for clarity. Residues that contribute ≥5.5% of ORG27569's total interaction energy are shown in orange. This includes F3.25189. K3.28192 is shown in bright orange; K3.28192 is shown forming a hydrogen bond (yellow dashes) with ORG27569.
