Table 1. Estimating the RBC age-specific burst sizes for individual genotypes.

Genotype, treatment	Average burst size	Relative proportion of infected reticulocytes	Estimated reticulocyte burst size	Estimated mature RBC burst size
More virulent, AS			36.79	5.38
Control	5.72	.011
PHZ	6.69	.042
Less virulent, DK			19.39	4.81
Control	5.04	.015
PHZ	5.32	.035

Note: Average burst sizes and relative proportions of infected reticulocytes represent experimental measurements. Red blood cell (RBC) age-specific burst sizes are estimated from these measures by asking, what do RBC age-specific burst sizes have to be if the increase in burst size between the control and PHZ treatments is entirely driven by the increase in the proportion of infected RBCs that are reticulocytes? The maximum burst size actually observed across all experimental infections was 12; therefore, higher burst sizes in reticulocytes cannot be the sole factor explaining the change in average burst size across the control and PHZ treatments.