TABLE ONE.
Microarray analysis of GADD45 family genes in chondrocytes treated with BMP-2
Subconfluent cultures of the immortalized human chondrocyte cell line, C-28/I2, were incubated for 1 h in the absence (control) or presence of 100 ng/ml of BMP-2. Total RNA was applied to the HU133A Affymetrix GeneChip.
Probe id | Gene | Control | BMP-2 | FC | LCB | Rank |
---|---|---|---|---|---|---|
207574_s_at | GADD45β | 285.86 | 832.17 | 2.91 | 2.71 | 13 |
209304_x_at | GADD45β | 420.60 | 1051.55 | 2.5 | 2.26 | 31 |
209305_s_at | GADD45β | 266.40 | 668.53 | 2.51 | 2.2 | 37 |
203725_at | GADD45α | 529.55 | 512.18 | −1.03 | −1 | NA |
204121_at | GADD45γ | 221.52 | 251.23 | 1.13 | 1.04 | NA |
Probe identification (id), Affymetrix identifier for separate probes on the microarray; FC, fold change between control and BMP-2-treated sample; LCB, lower confidence bound; NA, not applicable.