Skip to main content
. Author manuscript; available in PMC: 2014 Feb 28.
Published in final edited form as: Hum Mutat. 2008 Nov;29(11):1342–1354. doi: 10.1002/humu.20896

FIGURE 4.

FIGURE 4

Contour curve and grade risk estimates. A: Joint risk estimates averaged from 20 points spaced evenly along each selected contour curve at each of the three depths of alignment. Closed error bars give ±1 standard deviation from the joint risk estimate at the GD0 intercept. B: Joint risk estimates averaged from 20 evenly points spaced evenly along each linear 45° reference “contour line.” Closed error bars give ±1 standard deviation from the joint risk estimate at the GD0 intercept. C: Joint risk estimates averaged from 50 evenly spaced points within each grade. Open error bars give the 95th percentile confidence intervals, determined from 1,000 bootstrap samplings over the underlying data.