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. Author manuscript; available in PMC: 2014 Feb 28.
Published in final edited form as: Hum Mutat. 2008 Nov;29(11):1342–1354. doi: 10.1002/humu.20896

FIGURE 5.

FIGURE 5

Grade cross-comparisons.The value given in each cell is the probability, from bootstrap sampling, that the average joint risk estimate for missense substitutions falling into the lower numbered grade of the pair-wise comparison is greater than the average joint risk estimate for missense substitutions falling into the higher numbered grade. A: Using the alignment through frog. B: Using the alignment through puffer fish. C: Using the alignment through sea urchin.