Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
Adverse effects | |||||
Systematic review |
307 adults with cervical dystonia 3 RCTs in this analysis |
Dry mouth
45/203 (22%) with botulinum B toxin 3/104 (3%) with placebo |
OR 5.19 95% CI 2.69 to 10.03 P <0.00001 NNH 6 95% CI 6 to 8 |
Large effect size | placebo |
Systematic review |
307 adults with cervical dystonia 3 RCTs in this analysis |
Dysphagia
39/204 (19%) with botulinum B toxin (10,000 U) 3/104 (3%) with placebo |
OR 4.97 P <0.00003 NNH 8 95% CI 7 to 11 |
Moderate effect size | placebo |