Table 4.

Subgroup Analyses

Outcome	Moderator	Moderator Effect	Moderator x Treatment	Current Use	TMC vs. TAU	TMC+ vs. TAU	TMC+ vs. TMC
Abstinence Composite	Cocaine Use	x2=28.78 p< .0001	x2=5.28 p= .071	Yes	z= 2.03 p= .042	z= 1.48 p= .139	z= −0.63 p= .531
				No	z= −0.87 p= .385	z= −1.04 p= .297	z= −0.25 p= .803
	Alcohol Use	x2=15.91 p< .0001	x2=6.38 p= .041	Yes	z= 2.69 p= .007	z= 1.69 p= .091	z= −1.08 p= .282
				No	z= −0.68 p= .500	z= −0.47 p= .641	z= 0.17 p= .866
Cocaine Urine Toxicology	Cocaine Use	x2=14.24 p= .0002	x2=4.05 p= .132	Yes	z= −1.23 p= .218	z= −2.13 p= .033	z= −0.70 p= .483
				No	z= −0.58 p= .562	z= 0.76 p= .448	z= 1.36 p= .175
	Alcohol Use	x2=12.06 p= .0005	x2=0.08 p= .962	Yes	z= −0.84 p= .401	z= −0.88 p= .376	z= 0.00 p= .999
				No	z= −1.10 p= .271	z= −0.73 p= .468	z= 0.41 p= .684

Current use= use (yes/no) in 30 days prior to baseline (a period covering the week prior to IOP through the first 3 weeks of IOP). Moderator Effect refers to effect of moderator variable on the outcome variables. Moderator x Treatment refers to the effect of this interaction on the outcome variables.