Table 6. Sensitivity*, Specificity**, Positive and Negative Predictive Values, and Likelihood ratios for Moorfields Regression Analysis (n=number of eyes).
Moorfields Regression Analysis | Not at POAG endpoint (n) | Non POAG % | POAG endpoint (n) | POAG % | All (n) | Likelihood Ratio | Negative Predictive Value | Positive Predictive Value | |
---|---|---|---|---|---|---|---|---|---|
Result | Within normal limits | 615 | 0.78** | 32 | 0.50 | 647 | 0.64 | 0.95 | 0.05 |
Borderline | 114 | 0.14 | 13 | 0.20 | 127 | 1.41 | 0.90 | 0.10 | |
Outside normal limits | 64 | 0.08 | 19 | 0.30* | 83 | 3.68 | 0.77 | 0.23 | |
Global | Within normal limits | 726 | 0.92** | 42 | 0.66 | 768 | 0.72 | 0.95 | 0.05 |
Borderline | 55 | 0.07 | 15 | 0.23 | 70 | 3.38 | 0.79 | 0.21 | |
Outside normal limits | 12 | 0.02 | 7 | 0.11* | 19 | 7.23 | 0.63 | 0.37 | |
Nasal | Within normal limits | 721 | 0.91** | 45 | 0.70 | 766 | 0.77 | 0.94 | 0.06 |
Borderline | 44 | 0.06 | 10 | 0.16 | 54 | 2.82 | 0.81 | 0.19 | |
Outside normal limits | 28 | 0.04 | 9 | 0.14* | 37 | 3.98 | 0.76 | 0.24 | |
Nasal Inferior | Within normal limits | 704 | 0.89** | 44 | 0.69 | 748 | 0.77 | 0.94 | 0.06 |
Borderline | 65 | 0.08 | 9 | 0.14 | 74 | 1.72 | 0.88 | 0.12 | |
Outside normal limits | 24 | 0.03 | 11 | 0.17* | 35 | 5.68 | 0.69 | 0.31 | |
Nasal Superior | Within normal limits | 718 | 0.91** | 45 | 0.70 | 763 | 0.78 | 0.94 | 0.06 |
Borderline | 49 | 0.06 | 11 | 0.17 | 60 | 2.78 | 0.82 | 0.18 | |
Outside normal limits | 26 | 0.03 | 8 | 0.13* | 34 | 3.81 | 0.76 | 0.24 | |
Temporal | Within normal limits | 758 | 0.96** | 56 | 0.88 | 814 | 0.92 | 0.93 | 0.07 |
Borderline | 29 | 0.04 | 7 | 0.11 | 36 | 2.99 | 0.81 | 0.19 | |
Outside normal limits | 6 | 0.01 | 1 | 0.02* | 7 | 2.07 | 0.86 | 0.14 | |
Temporal Inferior | Within normal limits | 745 | 0.94** | 51 | 0.80 | 796 | 0.85 | 0.94 | 0.06 |
Borderline | 38 | 0.05 | 9 | 0.14 | 47 | 2.93 | 0.81 | 0.19 | |
Outside normal limits | 10 | 0.01 | 4 | 0.06* | 14 | 4.96 | 0.71 | 0.29 | |
Temporal Superior | Within normal limits | 757 | 0.48** | 50 | 0.78 | 807 | 1.64 | 0.94 | 0.06 |
Borderline | 31 | 0.04 | 6 | 0.09 | 37 | 2.40 | 0.84 | 0.16 | |
Outside normal limits | 5 | 0.00 | 8 | 0.13* | 13 | 39.65 | 0.38 | 0.62 |
POAG = Primary open angle glaucoma