Table 2.

Differentially expressed genes in RFC1^+/+ and RFC1^+/− mice

Accession no.	Symbol	Gene description	Fold change, heterozygous/wild-type	P
Transcription/translation
NM_011543	Skp1a	S-phase kinase-associated protein 1A	0.44	0.04
NM_009099	Trim30	Tripartite motif protein 30	0.36	0.01
Immune response
NM_010724	Psmb8	Proteosome (prosome, macropain) subunit, β type 8 (large multifunctional protease 7)	0.43	0.05
NM_010738	Ly6a	Lymphocyte antigen 6 complex, locus A	0.49	0.04
G-protein signaling
NM_008330	Olfr56	Olfactory receptor 56	0.49	0.01
NM_007588	Calcr	Calcitonin receptor	2.85	0.04
Others
NM_013864	Ndr2	N-myc downstream regulated 2 (cell differentiation)	2.17	0.04

NOTE: Genes were selected based on a significant (P < 0.05) and a differential fold change in expression >2 or <0.5. From each genotype, colonic mucosa from three noninjected (100-day-old baseline) mice was collected and processed for RNA isolation. Fold change refers to the normalized signal intensity of a given gene in RFC1^+/− (heterozygous) relative to RFC1^+/+ (wild-type) mice.