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. Author manuscript; available in PMC: 2014 Feb 28.
Published in final edited form as: Compr Physiol. 2011 Jul;1(3):1603–1648. doi: 10.1002/cphy.c100059

Table 3.

Effects of training and genotype-training interactions in the response to high-intensity intermittent training for muscle fiber types and enzyme activities

Enzyme Before training mean ± SD After training mean ± SD Genotype-training interaction F ratio Intrapair resemblance in response
CK 237.0 ± 48 278.0 ± 98 9.8** 0.82
HK 1.3 ± 0.4 1.41 ± 0.36 3.8* 0.59
PFK 152.0 ± 27 155.0 ± 52 2.2 0.38
LDH 239.0 ± 122 201.0 ± 93 4.6** 0.64
MDH 220.0 ± 56 246.0 ± 44* 3.0* 0.50
HADH 3.7 ± 1.2 5.03 ± 1.55** 1.3 0.15
OGDH 0.7 ± 0.2 1.04 ± 0.23** 3.0* 0.50
PFK/OGDH ratio 558.0 ± 173 231.0 ± 109 4.5** 0.64

All enzymes were expressed in μmol of NADH or NADPH per gram of wet weight per minute.

n=12 pairs of MZ twins. HADH=3-hydroxyacyl CoA dehydrogenase, CK=creatine kinase, HK=hexokinase, LDH=lactate dehydrogenase, MDH=malate dehydrogenase, OGDH=oxoglutarate dehydrogenase, PFK=phosphofructokinase.

*

p < 0.05

**

p < 0.01

From Simoneau, J.A. et al. (1986) Inheritance of human skeletal muscle and anaerobic capacity adaptation to high-intensity intermittent training. International Journal of Sports Medicine 7, 167–171. Reproduced with permission from Thieme.