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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Trends Genet. 2013 Jan 9;29(5):280–289. doi: 10.1016/j.tig.2012.12.002

Figure 2. Bioinformatic MEI identification methods.

Figure 2

A) Anchored read-pair mapping. Targeted MEIs are shown as green boxes. The flanking genomic sequence is shown as black bar (5’) or grey bar (3’), respectively. The paired-end reads are shown in arrows with patterns matching the corresponding genomic regions. The arrows indicate the direction of the read. The middle of the DNA fragment that is not sequenced is shown as dotted lines. B) Split-read mapping. Reads are shown in arrows with patterns matching the corresponding genomic regions. The top read illustrates a long sequence read that covers the whole MEI and both TSDs. This type of read provides the highest confidence in MEI inference.