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. Author manuscript; available in PMC: 2014 Feb 28.
Published in final edited form as: Chin Sci Bull. 2012 Aug 18;57(31):3961–3971. doi: 10.1007/s11434-012-5387-5

Table 1.

Nanoparticle
Function
Subfunctions Types of
Nanoparticles
General Medical
Application
Refs
Drug Delivery Delayed release
Drug solubilization
Porous silica
Porous silicon
Liposomes
Micelles
Polymer-based NP
Deliver drugs to toxic or pathologic cells [79, 80]
Specific Targeting Immunotargeting
Receptor mediated
Passive targeting
Porous silica
Porous silicon
Liposomes
Micelles
Polymer-based NP
Translocate particles within the body to a specific site [79, 81]
Triggered Release pH responsive
Thermo responsive
Electro responsive
Ultrasound induced release
Liposomes
Polymer-based NP
Hydrogels
Control the release of a drug or action of a nanoparticle in a spatiotemporal manner [82, 83]
Thermal Ablation Photothermal ablation Gold nanoshells
Super-paramagnetic iron oxide NP
Heat up cells or tissue near NP sites [84, 85]
Contrast Agents MRI agents
X-ray enhancers
Ultrasound
Gadolinium NP
Super-paramagnetic iron oxide NP
Enhance radiological studies [86, 87]
Magnetism Localized heating
Particle accumulation
Super-paramagnetic iron oxide NP Control particles via magnetic fields outside the body [88, 89]