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. 2014 Feb 17;124(3):1083–1097. doi: 10.1172/JCI70391

Figure 6. The Cdkn2b-dependent defect in efferocytosis is reversible.

Figure 6

(A) Application of exogenous CALR peptide abrogates the baseline difference in engulfment rates observed between Cdkn2b–/– ABs and Cdkn2b+/+ ABs. Exogenous CALR peptide also normalizes the baseline differences in Abca1 expression (B) and foam cell formation (C). Original magnification, ×20. #P < 0.01; P < 0.03.