Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
X-ray co-crystal structure of Star 12 bound to the kinase domain of Src-AS1. The iso-butyl group of Star 12 projects towards the expanded gatekeeper pocket (orange). The N12-butylamine group forms hydrogen bonds with side chain of Asn 391 and the backbone carbonyl of Ala 390.
