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. 2013 Jul 16;29(3):522–528. doi: 10.1093/ndt/gft270

FIGURE 3:

FIGURE 3:

Fate of the HSCs after transplantation in the Ctns−/− mice. HSCs migrate to the injured tissues and differentiate into tissue-resident phagocytic cells. The question that remains unsolved is how these cells lead to tissue rescue? Is it by phagocytizing the cystine-overloaded cells, by transferring the functional cystinosin to adjacent cells or by another pathway?