Table 1.
Demographic characteristics of unrelated African American non-diabetic ESKD cases and non-nephropathy controls
| Group | # APOL1 risk variants | n | Age at recruitment, years |
African ancestry, % |
Age at ESKD, years |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SD | Median | Mean | SD | Median | Mean | SD | Median | |||
| Controls | 0/1 | 1283 | 49.4 | 12.0 | 48.5 | 0.77 | 0.11 | 0.79 | NA | NA | NA |
| 2 | 221 | 49.6 | 13.7 | 48.0 | 0.80 | 0.09 | 0.81 | NA | NA | NA | |
| All | 1504 | 49.4 | 12.3 | 48.0 | 0.77 | 0.11 | 0.79 | NA | NA | NA | |
| ESKD cases | 0/1 | 726 | 57.5 | 14.1 | 57.0 | 0.80 | 0.11 | 0.81 | 53.9 | 38.3 | 52.0 |
| 2 | 641 | 51.4 | 13.8 | 51.0 | 0.80 | 0.09 | 0.81 | 45.2 | 14.8 | 44.0 | |
| All | 1367 | 54.6 | 14.3 | 54.0 | 0.80 | 0.10 | 0.81 | 49.8 | 30.0 | 49.0 | |
| Combined | 0/1 | 2009 | 52.6 | 13.5 | 51.0 | 0.78 | 0.11 | 0.80 | 53.9 | 38.3 | 52.0 |
| 2 | 862 | 51.0 | 13.8 | 50.0 | 0.80 | 0.09 | 0.81 | 45.2 | 14.8 | 44.0 | |
| All | 2871 | 52.1 | 13.6 | 51.0 | 0.79 | 0.11 | 0.80 | 49.8 | 30.0 | 49.0 | |