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Renal function evaluation of patients with O104:H4 E. coli HUS at the onset of diarrhoea, diagnosis of STEC-HUS and after initiation of eculizumab treatment. Coloured bars: grading of AKI according to the Acute Kidney Injury Network [30]. Closed circles and lines: evolution of median and range serum creatinine concentrations. At Day 42 after initiation of eculizumab treatment, serum creatinine had returned to baseline values.
