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. 2014 Feb 28;9(2):e86716. doi: 10.1371/journal.pone.0086716

Figure 3. Freezing Artifacts.

Figure 3

Artifactual acute lung injury probably related to tissue damage from cold consisting in edema, intra-alveolar fibrin and blood. The lesion is seen in the lower left corner, consisting in an area of patchy fibrosis with some chronic inflammation and a fibroblastic focus (UIP with high confidence).