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. 2014 Feb 28;9(2):e89561. doi: 10.1371/journal.pone.0089561

Table 2. Spontaneous incidence of type 1 diabetes at 7 months of age compared to anti PDL1 treatment of 10 week old mice.

Strain Line Cumulative Incidence of spontaneous type 1 diabetes Cumulative Incidence of type 1 diabetes with aPDL1 treatment starting at 10 weeks
NOD.B10-Idd5.1 1094 40% 62.5%
Idd5.2 Idd5.3
NOD.B10-Idd5.1 2193 62% 66%
NOD.B10-Idd5.2 6146 38% 80%
NOD.B10-Idd5.3 6360 69% 90%
NOD.B10-Idd5.2 1595 25% 65%
Idd5.3
NOD.B10- 905 3% 46%
Idd9.1/9.2/9.3
NOD.B10-Idd9.1 1565 35% 95%
NOD.B10-Idd9.2 1566 55% 56%
NOD.B10-Idd9.3 1106 50% 90%
NOD.B6-Idd3 1098 20% 50%
NOD.B6- 7754 50% 94%
Idd10/Idd18
NOD.B6-Idd3/10/18 1538 9% 31%
NOD.B6-Idd3 B10- 6109 1% 0%
Idd5
NOD.B6-Idd3 7380 0% 15%
Idd5.2/5.3
NOD.B6-Idd3 9245 0%
Idd5.2/5.3
NOD 70–90% 93%