Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Feb 24;8:435–440. doi: 10.2147/OPTH.S58164

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Kuroda et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

SD-OCT images of normal and RP retinas. (A) In the image of a normal eye (reduced speckle noise), the boundaries of the retinal layers are well demarcated. (B) In the image of an RP eye, some pathological findings were observed. (1) Defects of the IS/OS junction and ELM reflex, (2) thinning of the ONL, (3) thinning of the reflex of the RPE-Bruch’s membrane complex, (4) HFs in the INL, and (5) HFs in the ONL and subretinal space. (C) RP retina without HFs in the ONL. In this eye, no thinning of the reflex of RPE-Bruch’s membrane complex was observed. (D) In four cases, the ONL (white arrow) seemed to be preserved over a wider area than the RPE-Bruch’s membrane complex (shown in bold bracket). (E) RP retinas with HFs (arrowheads) in the ONL. All RP eyes with no IS/OS under the fovea had HFs in the ONL.

Abbreviations: RNFL, retinal nerve fiber layer; IPL, inner plexiform layer; INL, inner nuclear layer; OPL, outer plexiform layer; GCL, ganglion cell layer; RPE/BM, retinal pigment epithelium and Bruch’s membrane complex; COST, cone outer segment tips; IS/OS, inner segment/outer segment junction of photoreceptors; ELM, external limiting membrane; ONL, outer nuclear layer; SD-OCT, spectral-domain optical coherence tomography; RP, retinitis pigmentosa; HFs, hyperreflective foci.