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(A and B) The antiproliferative effect of celecoxib combined with gefitinib was evaluated in HepG2 multicellular spheroids and monolayer cells. (A) HepG2 multicellular spheroids; (B) HepG2 monolayer cells. Gefitinib (5 μmol/L) increased the inhibitory effect of celecoxib.
Notes: *P<0.05, gefitinib plus celecoxib versus celecoxib. All sample measurements were replicated five times.
