Table 2. Correlation of QKI-5 with clinicopathologic characteristics of patients with PCa.
Variable | N | QKI mRNA expression | P | |||
---|---|---|---|---|---|---|
Reduced | % | Unreduced | % | |||
Age at diagnosis | 0.954a | |||||
≥60 | 120 | 83 | 69.20% | 37 | 30.80% | |
<60 | 64 | 44 | 68.80% | 20 | 31.20% | |
Gleason score | <0.001b | |||||
2:4 | 27 | 11 | 40.70% | 16 | 59.30% | |
5:7 | 63 | 39 | 61.90% | 24 | 38.10% | |
8:10 | 94 | 77 | 81.90% | 17 | 18.10% | |
PSA in serum | 0.457a | |||||
>20 ng/ml | 156 | 106 | 67.90% | 50 | 32.10% | |
≤20 ng/ml | 28 | 21 | 75.00% | 7 | 25.00% | |
Differentiation status | <0.001a | |||||
Well | 25 | 9 | 36.00% | 16 | 64.00% | |
Moderately | 66 | 43 | 65.20% | 23 | 34.80% | |
Poor and undifferentiatedly | 93 | 75 | 80.60% | 18 | 19.40% | |
Depth of invasion | 0.050a | |||||
pT1+pT2 | 52 | 28 | 53.80% | 24 | 46.20% | |
pT3+pT4 | 132 | 99 | 75.00% | 33 | 25.00% | |
Lymph node metastasis | 0.001a | |||||
Absent (N0) | 81 | 46 | 56.80% | 35 | 43.20% | |
Present (N1:3) | 103 | 81 | 78.60% | 22 | 21.40% | |
Distant metastasis | 0.001a | |||||
Absent (M0) | 142 | 87 | 62.30% | 55 | 37.70% | |
Present (M1) | 42 | 40 | 95.20% | 2 | 4.80% | |
pTNM stage | <0.001b | |||||
I | 21 | 5 | 23.80% | 16 | 76.20% | |
II | 27 | 16 | 59.30% | 9 | 40.70% | |
III | 79 | 59 | 74.70% | 18 | 25.30% | |
IV | 57 | 47 | 82.50% | 10 | 17.50% |
aP value when expression levels were compared using the Pearson χ2 test. bP value when expression levels were compared using Mann–Whitney U test.