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. 2014 Feb 28;9(2):e89798. doi: 10.1371/journal.pone.0089798

Table 2. The associations between use of antithrombotics with aggravation of hemorrhagic transformation by multivariate logistic regression analysis in patients with hemorrhagic infarction (N = 150).

Model 1 p Model 2 p
Anti-thrombotics before HT 0.467 0.475
No med Ref Ref
Antiplatelet 0.489 (0.117–2.049) 0.328 0.508 (0.120–2.147) 0.357
Warfarin 0.965 (0.199–4.679) 0.965 1.021 (0.206–5.053) 0.980
Anti-thrombotics after HT 0.038 0.041
No med Ref Ref
Antiplatelet 0.150 (0.035–0.642) 0.011 0.153 (0.036–0.657) 0.012
Warfarin 0.517 (0.124–2.152) 0.365 1.186 (0.375–3.755) 0.771

Aggravation of HT; Model 1: Adjusted by age and initial NIHSS. Model 2: Adjusted by age, initial NIHSS, and thrombolysis.

END; adjusted by age, initial NIHSS and thrombolysis.