Table 4. Dmax, Dmean and Dmin of various OARs in IMRT plans with and without HPC sparing.
ORA | Parameter | Non-sparing (Gy) | Sparing (Gy) | P-value |
Lenses | Dmax | 6.56±0.88 | 6.49±0.74 | 0.48 |
Dmean | 4.63±0.74 | 4.64±0.72 | 0.35 | |
Dmin | 3.55±0.67 | 3.58±0.64 | 0.65 | |
Eyes | Dmax | 36.38±3.67 | 33.75±4.23 | 0.03 |
Dmean | 7.21±0.84 | 6.85±0.83 | 0.00 | |
Dmin | 1.90±0.23 | 1.91±0.24 | 0.60 | |
Temporal lobes | Dmax | 67.83±2.36 | 67.69±2.43 | 0.48 |
Dmean | 20.74±4.06 | 19.95±3.97 | 0.01 | |
Dmin | 1.55±0.38 | 1.51±0.38 | 0.04 | |
Brain-stem | Dmax | 53.06±0.40 | 53.00±0.44 | 0.18 |
Dmean | 35.59±0.84 | 35.66±0.85 | 0.09 | |
Dmin | 9.19±0.30 | 9.23±0.30 | 0.44 | |
Optic Nerves | Dmax | 47.25±1.80 | 46.60±1.81 | 0.08 |
Dmean | 24.03±4.00 | 24.29±3.97 | 0.04 | |
Dmin | 6.51±0.85 | 6.76±0.93 | 0.03 | |
Optic Chiasm | Dmax | 48.15±1.56 | 46.63±1.59 | 0.00 |
Dmean | 23.61±1.22 | 21.09±1.09 | 0.00 | |
Dmin | 9.56±2.75 | 8.58±2.58 | 0.00 | |
Cochleae | Dmax | 58.54±3.62 | 58.19±3.60 | 0.06 |
Dmean | 42.89±1.53 | 43.39±1.72 | 0.01 | |
Dmin | 32.88±2.35 | 32.94±2.19 | 0.73 | |
Spinal Cord | Dmax | 42.76±0.97 | 42.74±0.93 | 0.52 |
Dmean | 25.34±1.31 | 25.31±1.26 | 0.35 | |
Dmin | 0.40±0.15 | 0.40±0.16 | 0.35 |
Data presented as mean±standard deviation. Two-tailed P values from paired t tests. Abbreviation: Dmax = maximum dose; Dmean = mean dose; Dmin = minimum dose.