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. 2014 Feb 28;9(2):e90122. doi: 10.1371/journal.pone.0090122

Figure 4. RBL-2H3 cells' degranulation inhibition by naphthoquinones.

Figure 4

Effect on cell viability and β-hexosaminidase and histamine release in (A) IgE-antigen- or in (B) calcium ionophore (A23187)-stimulated cells treated with quercetin (QCT) and naphthoquinones [diospyrin (DPR), diosquinone (DQN), juglone (JGL), menadione (MND), naphthazarin (NTZ) and plumbagin (PLB)], n = 3–10. *P<0.05, paired t test to respective control (100 ng/mL IgE/DNP + 0.1% DMSO or 1 µM A23187 + 0.5% DMSO).