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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Hepatology. 2014 Apr 1;59(5):1761–1771. doi: 10.1002/hep.26714

Figure 2. Hepatic expression of CES1 selectively regulates gene expression and has no effect on lipogenesis or VLDL secretion.

Figure 2

(A) Hepatic mRNA levels in wild-type (left panel) or ob/ob mice (right panel) were determined by qRT-PCR. (B–D) De novo lipogenesis was determined in mice after injection of 2H2O (n=5 mice per group). The levels of newly synthesized [2H]palmitate (B), [2H]TG (C) or [2H]cholesterol (D) in the liver were quantified. (E) Hepatic protein level was assessed by Western blot assays. (F) VLDL secretion rate was determined (n=6 mice per group).