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. 2014 Feb 28;9(2):e90093. doi: 10.1371/journal.pone.0090093

Figure 6. GLP-1 total content and Western Blot analysis for Pax6 and PC1/3 in pancreatic rat islets chronically exposed to Exendin-4.

Figure 6

Panel (A) shows the total intracellular GLP-1 content of pancreatic rat islets cultured in the presence or absence of Exendin-4 (100 nmol/l) for 72 hours. The data are expressed as means ± SE. ** p<0.01 vs. control group. Panel (B) the upper side shows a representative Western Blot for the Pax6 protein in rat pancreatic islets cultured in the presence or absence of Exendin-4 (100 nmol/l) for 72 hours; the lower side shows the densitometric analysis (means from five different Western Blot experiments). The data are expressed as means ± SE. ** p<0.01 vs. control groups. Panel (C) the upper side of shows a representative Western Blot for PC1/3 protein expression in pancreatic rat islets cultured in the presence or absence of Exendin-4 (100 nmol/l) for 72 hours; the lower side shows the densitometric analysis (means from five different Western Blot experiments). The data are expressed as the means ± SE. * p<0.05 vs. control groups.