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. 2014 Feb 28;9(2):e90150. doi: 10.1371/journal.pone.0090150

Figure 1. Gene expression responses to exercise are not significantly different between COPD patients and healthy controls, regardless of desaturation status.

Figure 1

A Gene expression inductions (post/pre) for regulators of Oxphen. PPAR, peroxisome proliferator-activated receptor; PGC, PPAR gamma co-activator; PRC, PGC-1-related co-activator; ERRα, estrogen-related receptor α; NRF, nuclear respiratory factor; TFAM, mitochondrial transcription factor A. B Gene expression inductions for metabolic enzymes involved in citric acid cycle, β-oxidation and glycolysis. CS, citrate synthase; HADH, 3-hydroxyacyl-CoA dehydrogenase; COX4-1, cytochrome c oxidase subunit IV isoform 1; HK-II, hexokinase II; PFK, phosphofructokinase muscle isoform. C Gene expression inductions of hypoxia-associated targets. HIF-1α, hypoxia-inducible factor 1 alpha; VEGF-A, vascular endothelial growth factor A; GLUT1, glucose transporter 1. Whiskers indicate minimum and maximum values. Level of significance: *p<0.05 for post vs. pre.