Table 4.
Laboratory factors for IVIG resistance in children with Kawasaki disease
| Variables |
IVIG response |
IVIG resistance |
P value |
|---|---|---|---|
| (n = 47) | (n = 17) | ||
| WBC (/mm3) |
13,990 (4,000 ~ 28,000) |
18,710 (7,460 ~ 30,300) |
0.323 |
| Neutrophils (%) |
79.1 (29.3 ~ 95.2) |
83.9 (63.6 ~ 95.3) |
0.342 |
| Hemoglobin (g/dL) |
11.6 (9.2 ~ 14.8) |
12.2 (8.7 ~ 14.3) |
0.460 |
| Platelet count (/mm3) |
323,000 (64,000 ~ 573,000) |
287,000 (94,000 ~ 513,000) |
0.861 |
| Albumin (g/dL) |
3.8 (2.6 ~ 4.4) |
3.7 (3.0 ~ 4.6) |
0.801 |
| Total bilirubin (mg/dL) |
1.7 (0.2 ~ 5.7) |
2.5 (0.6 ~ 4.7) |
0.164 |
| Direct bilirubin (mg/dL) |
2.1 (0.1 ~ 5.3) |
2.2 (1.8 ~ 4.1) |
0.595 |
| AST (IU/L) |
128 (19 ~ 1,287) |
88 (34 ~ 646) |
0.837 |
| ALT (IU/L) |
172 (6 ~ 1,076) |
168 (18 ~ 1,027) |
0.677 |
| γGT (IU/L) |
227.5 (20 ~ 577) |
160.0 (105 ~ 258) |
0.365 |
| ESR (mm/h) |
38 (3 ~ 120) |
47 (30 ~ 72) |
0.499 |
| CRP (mg/dL) |
8.3 (0.2 ~ 26.0) |
10.9 (4.7 ~ 26.0) |
0.354 |
| PT INR |
1.2 (1.0 ~ 10.9) |
1.33 (1.1 ~ 1.5) |
0.024* |
| aPTT (sec) | 44.2 (26.8 ~ 58.7) | 45.0 (41.8 ~ 55.0) | 0.682 |
Data are presented as median (range).
*p < 0.05.
aPTT, activated partial thromboplastin time; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CI, confidence interval; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; γGT, gamma glutamyl transferase, INR, international normalized ratio; PT, prothrombin time; WBC, white blood cell.