Table 1.
The Effects of Growth Factors Supplement on the Development of Human r2PN Zygotes
| Growth factors | Develop to | |||||
|---|---|---|---|---|---|---|
| EGF | BDNF | IGF-1 | No. of r2PN zygotes | 2C | 8C | B |
| − | − | − | 58 | 53 (91.4)a | 19 (32.8)a | 6 (10.3)a |
| + | − | − | 33 | 31 (93.9)a | 12 (36.4)a | 3 (9.7)a |
| − | + | − | 32 | 29 (90.6)a | 11 (34.4)a | 2 (6.3)a |
| − | − | + | 30 | 27 (90.0)a | 11 (36.7)a | 2 (6.8)a |
| + | + | − | 35 | 33 (94.3)a | 15 (42.9)a, | 6 (17.1)a |
| + | − | + | 34 | 30 (88.2)a | 14 (41.2)a, | 5 (14.7)a |
| − | + | + | 30 | 28 (93.3)a | 13 (46.7)a | 2 (7.1)a |
| + | + | + | 48 | 45 (93.8)a | 29 (60.4)b | 13 (27.1)b |
Values with different superscripts in the same column differ significantly (P<0.05).
EGF, epidermal growth factor; BDNF, brain-derived neurotrophic factor; IGF-1, insulin-like growth factor-1.