Table 1.
Demographics, radiological, and physiological and biological data at baseline
| Total | Initiation of invasive ventilation | |||
|---|---|---|---|---|
|
| ||||
| Number of FOB procedures | 169 | No | Yes | p |
|
| ||||
| 144 | 25 | |||
| Age (years) | 59 [23–91] | 59 [23–88] | 64.5 [35–91] | 0.723 |
| Gender (% males) | 115 (68) | 98 (68) | 17 (68) | 0.996 |
| BMI (kg/m2) | 23 [14–38] | 24 [14–38] | 22 [17–35] | 0.198 |
|
| ||||
| Interstitial opacities (%) | 43 (26) | 36 (26) | 7 (28) | 0.749 |
| Bilateral opacities (%) | 63 (38) | 51 (36) | 12 (48) | 0.451 |
| Pleural syndrome (%) | 28 (17) | 24 (17) | 4 (16) | 0.888 |
|
| ||||
| SAPS II | 38 [6–99] | 37 [6–81] | 43 [19–99] | 0.107 |
| ODIN | 2 [0–8] | 2 [0–8] | 2 [1–6] | 0.118 |
|
| ||||
| RR (breaths/min) | 26 [14–52] | 26 [14–52] | 30 [18–50] | 0.043* |
| HR (beats/min) | 98 [47–155] | 97 [47–155] | 112 [74–132] | 0.014* |
| SBP (mmHg) | 127 [69–191] | 127 [69–191] | 125 [92–172] | 0.689 |
| PaO2/FiO2 (mmHg) | 194 [61–300] | 196 [61–300] | 184 [92–293] | 0.819 |
| PaO2 (mmHg) | 72 [39–167] | 70 [39–167] | 78 [44–132] | 0.492 |
| FiO2 (%) | 53 [25–100] | 50 [25–100] | 60 [25–100] | 0.197 |
| PaCO2 (mmHg) | 40 [24–91] | 40 [24–91] | 37 [24–80] | 0.245 |
| PT (%) | 76 [14–100] | 77 [14–100] | 71 [37–100] | 0.276 |
| Platelets (giga/ml) | 253 [6–740] | 258 [6–740] | 236 [41–663] | 0.378 |
| Blood Urea (mmol/l) | 7 [1.5–47] | 7 [1.5–47] | 10.9 [2.8–39.2] | 0.198 |
| Serum Creatinin (μmol/l) | 79 [30–664] | 78 [30–601] | 93 [32–664] | 0.760 |
Results are given either as number (percentages) or median (minimal and maximal values).
Abbreviations: FOB, fibreoptic bronchoscopy; BMI, body mass index; SAPS II, Simplified Acute Physiologic Score II; ODIN, Organ Dysfunction and Infection score; PaO2/FiO2, ratio of partial oxygen pressure in arterial blood over inspired fraction of oxygen; PaCO2, partial carbon dioxide pressure in arterial blood; RR, respiratory rate; HR, heart rate; SBP, systolic blood pressure; PT, prothrombin time.
*
p<0.05.