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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Nat Neurosci. 2013 Jun 30;16(8):1094–1100. doi: 10.1038/nn.3445

Figure 1.

Figure 1

Inhibition of NMDARs in the NAcore reduced aversion-resistant alcohol intake. (a) Intra-NAcore infusion of AP5 (0.5 μl per side of 1 μg μl−1) reduced intake, relative to that in saline-infused rats, of quinine-adulterated alcohol but not quinine-free alcohol in rats drinking alcohol 20 min d−1, 5 d week−1. (b) Similar results were observed when examining the impact of intra-NAcore AP5 on alcohol intake during the first 30 min of an intermittent overnight alcohol intake session (see Online Methods). Tukey post hoc *P < 0.05. Error bars indicate s.e.m.