Table 3.
Toxicity | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | |||||
---|---|---|---|---|---|---|---|---|---|---|
| ||||||||||
No. of Patients | % | No. of Patients | % | No. of Patients | % | No. of Patients | % | No. of Patients | % | |
Anemia | 18 | 82 | 5 | 15 | 5 | 15 | 0 | 0 | ||
Leukopenia | 11 | 32 | 8 | 24 | 5 | 15 | 4 | 12 | 0 | |
Thrombocytopenia | 11 | 32 | 0 | 1 | 3 | 3 | 9 | 0 | ||
Neutropenia | 13 | 38 | 4 | 12 | 6 | 18 | 10 | 29 | 0 | |
Allergy | 10 | 29 | 1 | 3 | 0 | 0 | 0 | |||
Auditory | 1 | 3 | 0 | 0 | 0 | 0 | ||||
Cardiovascular | 5 | 15 | 5 | 15 | 1 | 3 | 0 | 0 | ||
Impaired coagulation | 4 | 12 | 0 | 2 | 6 | 0 | 0 | |||
Constitutional | 9 | 26 | 17 | 50 | 5 | 15 | 0 | 1 | 3 | |
Rash | 12 | 35 | 11 | 32 | 0 | 0 | 0 | |||
Endocrine | 0 | 1 | 3 | 0 | 0 | 0 | ||||
Hyperbilirubinemia | 0 | 0 | 0 | 0 | 0 | |||||
Gastrointestinal | 12 | 35 | 15 | 44 | 4 | 12 | 0 | 0 | ||
Genitourinary | 1 | 3 | 3 | 9 | 2 | 6 | 0 | 0 | ||
Hemorrhage | 3 | 9 | 0 | 1 | 3 | 0 | 0 | |||
Infection/Febrile Neutropenia | 3 | 9 | 10 | 29 | 0 | 1 | 3 | 0 | ||
Lymphatics | 0 | 0 | 1 | 3 | 0 | 0 | 0 | |||
Metabolic | 12 | 35 | 11 | 32 | 7 | 21 | 1 | 3 | 0 | |
Musculoskeletal | 1 | 3 | 0 | 1 | 3 | 0 | 0 | |||
Neurologic | 8 | 24 | 12 | 6 | 1 | 3 | 0 | 0 | ||
Ocular | 6 | 18 | 0 | 0 | 0 | 0 | ||||
Pain | 5 | 15 | 17 | 50 | 6 | 18 | 1 | 3 | 0 | |
Pulmonary | 8 | 24 | 8 | 24 | 0 | 0 | 0 | |||
Vascular | 0 | 1 | 3 | 2 | 6 | 0 | 0 |