Table 4.
Comparison of hormonal and sonographic markers of ovarian reserve in MS patients using only IFN-β with healthy controls
| MS patients (n=15 ) | Control (n=25 ) | P value | |
|---|---|---|---|
| Age (y) | 36 (23–39) | 32 (21–42) | 0.720 |
| BMI (kg/m2) | 24.39 (19.05–33.10) | 23.83 (19.0–34.5) | 0.408 |
| FSH (mIU/ml) | 6.56 (4.87–10.96) | 6.96 (4.21–14.37) | 0.820 |
| LH (mIU/ml) | 6.26 (3.49–11.90) | 4.96 (3.75–8.29) | 0.031 |
| E2 (pg/ml) | 48.04 (15.11–148.3) | 36.54 (17.6–192.8) | 0.604 |
| AFC (2–5 mm) | 5 (0–10) | 6 (2–16.5) | 0.074 |
| AFC (6–10 mm) | 2 (0–10) | 4 (2–9.5) | 0.001 |
| Total AFC (2–10 mm) | 7 (1.5–20) | 11 (6–23) | 0.002 |
| Ovarian volume (ml) | 5.34 (3.41–12.24) | 7.61 (3.61–15.79) | 0.009 |
Note: Data are median (range)
BMI: Body mass index. FSH: Follicle stimulating hormone. LH: Luteinizing hormone E2: Estradiol. AFC: Antral follicle count
Statistics were conducted by Mann Whitney-U test